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Gene : CXCR3 Homo sapiens

Name  ? C-X-C motif chemokine receptor 3 Cytological Location  Xq13.1
Brief Description  C-X-C motif chemokine receptor 3
Description  This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]
  • synonyms:
  • CKR-L2,
  • Mig-R,
  • MigR,
  • HGNC:4540,
  • CMKAR3,
  • G protein-coupled receptor 9,
  • CD183,
  • NM_001142797,
  • uc004eaf.3,
  • chemokine (C-X-C motif) receptor 3,
  • CXCR3,
  • CMKAR3,
  • CD182,
  • U32674,
  • GPR9,
  • CD183,
  • CKR-L2,
  • MigR,
  • IP10-R,
  • IP10-R,
  • OTTHUMG00000033326,
  • GPR9
  • identifiers:
  • 2833,
  • ENSG00000186810,
  • CXCR3

Genome feature

Region: gene ? Length: 2603  
Location: X:71615913-71618515 reverse strand Cyto location: Xq13.1


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Other

3 SNPs

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results