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Gene : ANGPT2 Homo sapiens

Name  ? angiopoietin 2 Cytological Location  8p23.1
Brief Description  angiopoietin 2
Description  The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Nov 2019]
  • synonyms:
  • Ang2,
  • OTTHUMG00000090365,
  • ANG2,
  • NM_001147,
  • ANGPT2,
  • AGPT2,
  • AF004327,
  • uc003wqj.6,
  • HGNC:485
  • identifiers:
  • 285,
  • ENSG00000091879,
  • ANGPT2

Genome feature

Region: gene ? Length: 63789  
Location: 8:6499632-6563420 reverse strand Cyto location: 8p23.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

38 SN Ps

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results