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Gene : ANGPT2 Homo sapiens

Name  ? angiopoietin 2 Cytological Location  8p23.1
Brief Description  angiopoietin 2
Description  This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome. [provided by RefSeq, Aug 2020]
  • synonyms:
  • uc003wqj.6,
  • AF004327,
  • HGNC:485,
  • Ang2,
  • AGPT2,
  • ANG2,
  • ANGPT2,
  • OTTHUMG00000090365,
  • NM_001147
  • identifiers:
  • 285,
  • ENSG00000091879,
  • ANGPT2

Genome feature

Region: gene ? Length: 63614  
Location: 8:6499632-6563245 reverse strand Cyto location: 8p23.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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38 SNPs

5 Cross References

16 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results