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Gene : GPR150 Homo sapiens

Name  ? G protein-coupled receptor 150 Cytological Location  5q15
Brief Description  G protein-coupled receptor 150
Description  This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]
  • synonyms:
  • BC030197,
  • PGR11,
  • HGNC:23628,
  • GPR150,
  • uc003kle.2,
  • NM_199243,
  • PGR11,
  • OTTHUMG00000121170
  • identifiers:
  • 285601,
  • ENSG00000178015,
  • GPR150

Genome feature

Region: gene ? Length: 2056  
Location: 5:95620087-95622142 Cyto location: 5q15

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



498 SN Ps

3 Cross References

12 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results