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Gene : DCPS Homo sapiens

Name  ? decapping enzyme, scavenger Cytological Location  11q24.2
Brief Description  decapping enzyme, scavenger
Description  This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover. [provided by RefSeq, Apr 2017]
  • synonyms:
  • HINT5,
  • HSL1,
  • 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase,
  • DCS1,
  • uc001qdp.3,
  • NM_014026,
  • OTTHUMG00000165829,
  • DCPS,
  • HSPC015,
  • HSPC015,
  • HGNC:29812,
  • HINT-5,
  • AF077201,
  • ARS,
  • HINT-5,
  • HSL1,
  • HINT5
  • identifiers:
  • 28960,
  • ENSG00000110063,
  • DCPS

Genome feature

Region: gene ? Length: 45946  
Location: 11:126304060-126350005 Cyto location: 11q24.2


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Gene -> HPO annotation (Human Phenotype Ontology)

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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3753 SN Ps

5 Cross References

20 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results