help  | about  | cite  | software

Gene : GRIK1 Homo sapiens

Name  ? glutamate ionotropic receptor kainate type subunit 1 Cytological Location  21q21.3
Brief Description  glutamate ionotropic receptor kainate type subunit 1
Description  Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • GLR5,
  • gluR-5,
  • GLUR5,
  • GluK1,
  • HGNC:4579,
  • NM_000830,
  • GLUR5,
  • glutamate receptor, ionotropic, kainate 1,
  • GRIK1,
  • EEA3,
  • OTTHUMG00000078879,
  • EAA3,
  • uc002ynn.4,
  • GluK1
  • identifiers:
  • 2897,
  • ENSG00000171189,
  • GRIK1

Genome feature

Region: gene ? Length: 403120  
Location: 21:29536933-29940052 reverse strand Cyto location: 21q21.3


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

402 SN Ps

5 Cross References

18 Data Sets

14 Homologues

0 Located Features

97 Rna Seq Results