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Gene : MRPS18B Homo sapiens

Name  ? mitochondrial ribosomal protein S18B Cytological Location  6p21.33
Brief Description  mitochondrial ribosomal protein S18B
description  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_014046,
  • MRPS18B,
  • HSPC183,
  • PTD017,
  • HumanS18a,
  • PTD017,
  • C6orf14,
  • uc063ynd.1,
  • MRP-S18-2,
  • HGNC:14516,
  • OTTHUMG00000031268,
  • MRPS18-2,
  • C6orf14,
  • MRPS18-2,
  • AF100761,
  • HSPC183,
  • S18amt
  • identifiers:
  • 28973,
  • ENSG00000204568,
  • MRPS18B

Genome feature

Region: gene ? Length: 9074  
Location: 6:30617320-30626393 Cyto location: 6p21.33

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



493 SN Ps

5 Cross References

13 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results