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Gene : GRIK2 Homo sapiens

Name  ? glutamate ionotropic receptor kainate type subunit 2 Cytological Location  6q16.3
Brief Description  glutamate ionotropic receptor kainate type subunit 2
Description  Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. [provided by RefSeq, Jul 2008]
  • synonyms:
  • GLUK6,
  • HGNC:4580,
  • GLUR6,
  • NM_001166247,
  • GLR6,
  • GRIK2,
  • MRT6,
  • uc003pqp.5,
  • GluK2,
  • OTTHUMG00000016328,
  • GLUR6,
  • glutamate receptor, ionotropic, kainate 2,
  • GluK2,
  • MRT6,
  • EAA4
  • identifiers:
  • 2898,
  • ENSG00000164418,
  • GRIK2

Genome feature

Region: gene ? Length: 676376  
Location: 6:101393708-102070083 Cyto location: 6q16.3


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SNPs

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Disease

1 Diseases

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3753 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results