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Gene : CXCL1 Homo sapiens

Name  ? C-X-C motif chemokine ligand 1 Cytological Location  4q13.3
Brief Description  C-X-C motif chemokine ligand 1
Description  This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
  • synonyms:
  • HGNC:4602,
  • MGSA,
  • melanoma growth stimulating activity, alpha,
  • GRO1,
  • NAP-3,
  • FSP,
  • SCYB1,
  • CXCL1,
  • fibroblast secretory protein,
  • MGSA-a,
  • MGSA-a,
  • GROa,
  • NM_001511,
  • OTTHUMG00000160866,
  • chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha),
  • GRO1 oncogene (melanoma growth stimulating activity, alpha),
  • GRO1,
  • J03561,
  • NAP-3,
  • GROa,
  • uc003hhh.4,
  • MGSA,
  • SCYB1,
  • FSP
  • identifiers:
  • 2919,
  • ENSG00000163739,
  • CXCL1

Genome feature

Region: gene ? Length: 1916  
Location: 4:73869393-73871308 Cyto location: 4q13.3

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



94 SN Ps

5 Cross References

16 Data Sets

12 Homologues

0 Located Features

97 Rna Seq Results