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Gene : GSR Homo sapiens

Name  ? glutathione-disulfide reductase Cytological Location  8p12
Brief Description  glutathione-disulfide reductase
Description  This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
  • synonyms:
  • OTTHUMG00000163946,
  • GR,
  • glutathione reductase,
  • GSRD,
  • uc003xih.3,
  • GSR,
  • glutathione S-reductase,
  • HGNC:4623,
  • NM_000637,
  • HEL-S-122m,
  • HEL-75
  • identifiers:
  • 2936,
  • ENSG00000104687,
  • GSR

Genome feature

Region: gene ? Length: 49939  
Location: 8:30678061-30727999 reverse strand Cyto location: 8p12


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Proteins

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SNPs

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Disease

1 Diseases

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Expression

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3753 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results