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Gene : GSTZ1 Homo sapiens

Name  ? glutathione S-transferase zeta 1 Cytological Location  14q24.3
Brief Description  glutathione S-transferase zeta 1
Description  This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, which is one of the steps in the phenylalanine/tyrosine degradation pathway. Deficiency of a similar gene in mouse causes oxidative stress. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq, Jul 2015]
  • synonyms:
  • U86529,
  • NM_145870,
  • GSTZ1-1,
  • HGNC:4643,
  • OTTHUMG00000171551,
  • uc001xtj.4,
  • maleylacetoacetate isomerase,
  • GSTZ1,
  • MAAI,
  • MAAID,
  • GSTZ1-1,
  • MAAI,
  • MAI,
  • MAI,
  • glutathione transferase zeta 1
  • identifiers:
  • 2954,
  • ENSG00000100577,
  • GSTZ1

Genome feature

Region: gene ? Length: 10596  
Location: 14:77321002-77331597 Cyto location: 14q24.3

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

18 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results