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Gene : GTF2A2 Homo sapiens

Name  ? general transcription factor IIA subunit 2 Cytological Location  15q22.2
Brief Description  general transcription factor IIA subunit 2
Description  Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).[supplied by OMIM, Mar 2008]
  • synonyms:
  • HsT18745,
  • TFIIA-12,
  • TF2A2,
  • general transcription factor IIA, 2, 12kDa,
  • HGNC:4647,
  • general transcription factor IIA, 2 (12kD subunit),
  • OTTHUMG00000132725,
  • T18745,
  • BC001919,
  • HsT18745,
  • TFIIA-gamma,
  • TFIIA gamma subunit,
  • GTF2A2,
  • general transcription factor IIA 2,
  • uc002agg.3,
  • TFIIA,
  • NM_004492,
  • identifiers:
  • 2958,
  • ENSG00000140307,
  • GTF2A2

Genome feature

Region: gene ? Length: 19454  
Location: 15:59638062-59657515 reverse strand Cyto location: 15q22.2

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3753 SN Ps

5 Cross References

15 Data Sets

8 Homologues

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97 Rna Seq Results