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Gene : ANAPC2 Homo sapiens

Name  ? anaphase promoting complex subunit 2 Cytological Location  9q34.3
Brief Description  anaphase promoting complex subunit 2
Description  A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000020983,
  • ANAPC2,
  • APC2,
  • KIAA1406,
  • uc004clr.2,
  • AB037827,
  • NM_013366,
  • APC2,
  • HGNC:19989
  • identifiers:
  • 29882,
  • ENSG00000176248,
  • ANAPC2

Genome feature

Region: gene ? Length: 13802  
Location: 9:137174784-137188585 reverse strand Cyto location: 9q34.3


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Function

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45 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

45 Pathways

398 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results