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Gene : CNOT7 Homo sapiens

Name  ? CCR4-NOT transcription complex subunit 7 Cytological Location  8p22
Brief Description  CCR4-NOT transcription complex subunit 7
Description  The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
  • synonyms:
  • CAF1,
  • BTG1 binding factor 1,
  • CAF-1,
  • CNOT7,
  • HGNC:14101,
  • CAF1,
  • OTTHUMG00000096971,
  • CCR4-NOT transcription complex, subunit 7,
  • hCAF-1,
  • Caf1a,
  • NM_013354,
  • L46722,
  • uc003wxg.2
  • identifiers:
  • 29883,
  • ENSG00000198791,
  • CNOT7

Genome feature

Region: gene ? Length: 24877  
Location: 8:17221981-17246857 reverse strand Cyto location: 8p22

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0 Diseases

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3740 SNPs

5 Cross References

15 Data Sets

6 Homologues

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97 Rna Seq Results