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Gene : GUSB Homo sapiens

Name  ? glucuronidase beta Cytological Location  7q11.21
Brief Description  glucuronidase beta
Description  This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.[provided by RefSeq, May 2014]
  • synonyms:
  • uc003tun.4,
  • M15182,
  • HGNC:4696,
  • MPS7,
  • BG,
  • GUSB,
  • NM_000181,
  • glucuronidase, beta,
  • OTTHUMG00000023735
  • identifiers:
  • 2990,
  • ENSG00000169919,
  • GUSB

Genome feature

Region: gene ? Length: 21547  
Location: 7:65960684-65982230 reverse strand Cyto location: 7q11.21


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

3753 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results