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Gene : GYPB Homo sapiens

Name  ? glycophorin B (MNS blood group) Cytological Location  4q31.21
Brief Description  glycophorin B (MNS blood group)
Description  Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  • synonyms:
  • OTTHUMG00000161404,
  • glycophorin B (Ss blood group),
  • GYPA,
  • GPB,
  • PAS-3,
  • GPB,
  • MNS,
  • SS,
  • uc003ijm.2,
  • HGNC:4703,
  • GYPB,
  • MNS,
  • NM_002100,
  • SS,
  • CD235b,
  • GYP,
  • glycophorin B (includes Ss blood group),
  • CD235b
  • identifiers:
  • 2994,
  • ENSG00000250361,
  • GYPB

Genome feature

Region: gene ? Length: 26690  
Location: 4:143995172-144021861 reverse strand Cyto location: 4q31.21


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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Other

3753 SN Ps

5 Cross References

17 Data Sets

1 Homologues

0 Located Features

97 Rna Seq Results