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Gene : A1CF Homo sapiens

Name  ? APOBEC1 complementation factor Cytological Location  10q11.23
Brief Description  APOBEC1 complementation factor
Description  Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  • synonyms:
  • ASP,
  • ACF64,
  • OTTHUMG00000018240,
  • A1CF,
  • ACF65,
  • uc057tgv.1,
  • ACF,
  • ACF,
  • NM_014576,
  • HGNC:24086,
  • ACF64,
  • ASP,
  • AF271790,
  • ACF65
  • identifiers:
  • 29974,
  • ENSG00000148584,
  • A1CF

Genome feature

Region: gene ? Length: 86258  
Location: 10:50799409-50885666 reverse strand Cyto location: 10q11.23

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



150 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results