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Gene : GZMB Homo sapiens

Name  ? granzyme B Cytological Location  14q12
Brief Description  granzyme B
Description  This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
  • synonyms:
  • T-cell serine protease 1-3E,
  • cytotoxic T-lymphocyte-associated serine esterase 1,
  • CCPI,
  • CTSGL1,
  • granzyme 2,
  • CGL1,
  • CTLA1,
  • NM_004131,
  • HGNC:4709,
  • CSPB,
  • CTLA1,
  • HLP,
  • SECT,
  • GZMB,
  • CSPB,
  • CGL1,
  • cytotoxic serine protease B,
  • CTSGL1,
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1),
  • CGL-1,
  • CSP-B,
  • CSP-B,
  • SECT,
  • fragmentin 2,
  • CCPI,
  • HLP,
  • BC030195,
  • cathepsin G-like 1,
  • C11,
  • CGL-1,
  • uc001wps.4,
  • OTTHUMG00000029369
  • identifiers:
  • 3002,
  • ENSG00000100453,
  • GZMB

Genome feature

Region: gene ? Length: 3237  
Location: 14:24630954-24634190 reverse strand Cyto location: 14q12


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Disease

0 Diseases

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Other

94 SN Ps

5 Cross References

17 Data Sets

21 Homologues

0 Located Features

97 Rna Seq Results