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Gene : GZMK Homo sapiens

Name  ? granzyme K Cytological Location  5q11.2
Brief Description  granzyme K
Description  This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000097009,
  • BC035802,
  • HGNC:4711,
  • tryptase II,
  • PRSS,
  • TRYP2,
  • GZMK,
  • uc003jpl.2,
  • granzyme K (granzyme 3; tryptase II),
  • granzyme K (serine protease, granzyme 3; tryptase II),
  • NM_002104,
  • TRYP2
  • identifiers:
  • 3003,
  • ENSG00000113088,
  • GZMK

Genome feature

Region: gene ? Length: 10315  
Location: 5:55024256-55034570 Cyto location: 5q11.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

249 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results