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Gene : H2AC8 Homo sapiens

Name  ? H2A clustered histone 8 Cytological Location  6p22.2
Brief Description  H2A clustered histone 8
Description  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]
  • synonyms:
  • NM_021052,
  • histone 1, H2ae,
  • M60752,
  • HIST1H2AE,
  • histone cluster 1 H2A family member e,
  • H2AFA,
  • H2A.2,
  • HIST1H2AE,
  • HGNC:4724,
  • H2A/a,
  • H2A.1,
  • uc003nha.3,
  • OTTHUMG00000014440,
  • H2A/a,
  • H2AC4,
  • H2A histone family, member A,
  • histone cluster 1, H2ae,
  • H2AFA,
  • H2AC8,
  • H2A.1
  • identifiers:
  • 3012,
  • ENSG00000277075,
  • H2AC8

Genome feature

Region: gene ? Length: 563  
Location: 6:26216921-26217483 Cyto location: 6p22.2

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86 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



86 Pathways

3753 SN Ps

5 Cross References

15 Data Sets

20 Homologues

0 Located Features

97 Rna Seq Results