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Gene : H2AZ1 Homo sapiens

Name  ? H2A.Z variant histone 1 Cytological Location  4q23
Brief Description  H2A.Z variant histone 1
Description  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]
  • synonyms:
  • H2A.z,
  • H2A/z,
  • H2A.Z,
  • H2A.Z-1,
  • H2AFZ,
  • OTTHUMG00000131048,
  • NM_002106,
  • H2AZ,
  • HGNC:4741,
  • H2AFZ,
  • X52317,
  • H2A histone family member Z,
  • H2A histone family, member Z,
  • H2AZ,
  • uc003hvo.2,
  • H2AZ1
  • identifiers:
  • 3015,
  • ENSG00000164032,
  • H2AZ1

Genome feature

Region: gene ? Length: 2188  
Location: 4:99948088-99950275 reverse strand Cyto location: 4q23


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74 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Proteins

Gene --> Proteins.

SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

74 Pathways

343 SN Ps

5 Cross References

17 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results