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Gene : HCRT Homo sapiens

Name  ? hypocretin neuropeptide precursor Cytological Location  17q21.2
Brief Description  hypocretin neuropeptide precursor
Description  This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]
  • synonyms:
  • OX,
  • PPOX,
  • HGNC:4847,
  • PPOX,
  • NRCLP1,
  • prepro-orexin,
  • NM_001524,
  • OTTHUMG00000180107,
  • HCRT,
  • AF041240,
  • OX,
  • uc002hzc.1,
  • hypocretin (orexin) neuropeptide precursor,
  • orexin
  • identifiers:
  • 3060,
  • ENSG00000161610,
  • HCRT

Genome feature

Region: gene ? Length: 1393  
Location: 17:42184060-42185452 reverse strand Cyto location: 17q21.2

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results