help  | about  | cite  | software

Gene : HDAC1 Homo sapiens

Name  ? histone deacetylase 1 Cytological Location  1p35.2-p35.1
Brief Description  histone deacetylase 1
Description  Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_004964,
  • uc001bvb.2,
  • KDAC1,
  • RPD3L1,
  • RPD3,
  • D50405,
  • HD1,
  • OTTHUMG00000007529,
  • HDAC1,
  • GON-10,
  • KDAC1,
  • HD1,
  • HGNC:4852,
  • GON-10,
  • RPD3L1
  • identifiers:
  • 3065,
  • ENSG00000116478,
  • HDAC1

Genome feature

Region: gene ? Length: 41546  
Location: 1:32292083-32333628 Cyto location: 1p35.2-p35.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

82 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



82 Pathways

107 SN Ps

5 Cross References

17 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results