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Gene : HDAC2 Homo sapiens

Name  ? histone deacetylase 2 Cytological Location  6q21
Brief Description  histone deacetylase 2
Description  This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
  • synonyms:
  • NM_001527,
  • KDAC2,
  • U31814,
  • HGNC:4853,
  • YAF1,
  • OTTHUMG00000015411,
  • HDAC2,
  • KDAC2,
  • YAF1,
  • RPD3,
  • HD2,
  • RPD3,
  • uc003pwd.3
  • identifiers:
  • 3066,
  • ENSG00000196591,
  • HDAC2

Genome feature

Region: gene ? Length: 38121  
Location: 6:113933028-113971148 reverse strand Cyto location: 6q21

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56 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



56 Pathways

138 SN Ps

5 Cross References

17 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results