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Gene : AOC2 Homo sapiens

Name  ? amine oxidase copper containing 2 Cytological Location  17q21.31
Brief Description  amine oxidase copper containing 2
Description  Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:549,
  • AOC2,
  • NM_001158,
  • NM_009590,
  • DAO2,
  • AF081363,
  • amine oxidase, copper containing 2 (retina-specific),
  • OTTHUMG00000180655,
  • RAO,
  • uc002ibu.5,
  • SSAO,
  • DAO2,
  • RAO
  • identifiers:
  • 314,
  • ENSG00000131480,
  • AOC2

Genome feature

Region: gene ? Length: 6128  
Location: 17:42844580-42850707 Cyto location: 17q21.31

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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525 SN Ps

5 Cross References

16 Data Sets

1 Homologues

0 Located Features

97 Rna Seq Results