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Gene : HNF4A Homo sapiens

Name  ? hepatocyte nuclear factor 4 alpha Cytological Location  20q13.12
Brief Description  hepatocyte nuclear factor 4 alpha
Description  The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
  • synonyms:
  • TCF,
  • HNF4alpha,
  • HNF4a8,
  • FRTS4,
  • TCF14,
  • X76930,
  • HNF4A,
  • HNF4,
  • NM_000457,
  • HNF4a9,
  • MODY1,
  • TCF14,
  • HGNC:5024,
  • MODY,
  • NR2A1,
  • OTTHUMG00000032531,
  • HNF4a7,
  • NR2A1,
  • MODY1,
  • NR2A21,
  • MODY,
  • uc002xlt.4,
  • HNF4
  • identifiers:
  • 3172,
  • ENSG00000101076,
  • HNF4A

Genome feature

Region: gene ? Length: 78898  
Location: 20:44355699-44434596 Cyto location: 20q13.12


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

3 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

87 SN Ps

5 Cross References

20 Data Sets

44 Homologues

0 Located Features

97 Rna Seq Results