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Gene : HNRNPD Homo sapiens

Name  ? heterogeneous nuclear ribonucleoprotein D Cytological Location  4q21.22
Brief Description  heterogeneous nuclear ribonucleoprotein D
Description  This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_031370,
  • AUF1,
  • AU-rich element RNA binding protein 1, 37kDa,
  • P37,
  • heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD),
  • HNRPD,
  • AUF1,
  • HNRPD,
  • HGNC:5036,
  • AUF1A,
  • OTTHUMG00000130290,
  • AF026126,
  • hnRNPD0,
  • uc003hmm.2
  • identifiers:
  • 3184,
  • ENSG00000138668,

Genome feature

Region: gene ? Length: 21499  
Location: 4:82352498-82373996 reverse strand Cyto location: 4q21.22

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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55 SN Ps

5 Cross References

17 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results