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Gene : APBA1 Homo sapiens

Name  ? amyloid beta precursor protein binding family A member 1 Cytological Location  9q21.12
Brief Description  amyloid beta precursor protein binding family A member 1
Description  The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000019984,
  • LIN10,
  • HGNC:578,
  • X11A,
  • uc004ahh.3,
  • amyloid beta (A4) precursor protein-binding, family A, member 1,
  • MINT1,
  • NM_001163,
  • X11,
  • AF029106,
  • X11,
  • X11ALPHA,
  • MINT1,
  • D9S411E,
  • APBA1,
  • D9S411E
  • identifiers:
  • 320,
  • ENSG00000107282,
  • APBA1

Genome feature

Region: gene ? Length: 245481  
Location: 9:69427532-69673012 reverse strand Cyto location: 9q21.12

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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674 SNPs

5 Cross References

15 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results