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Gene : HOXD10 Homo sapiens

Name  ? homeobox D10 Cytological Location  2q31.1
Brief Description  homeobox D10
Description  This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HOX4,
  • HOXD10,
  • uc002ukj.4,
  • OTTHUMG00000132511,
  • Hox-4.4,
  • HOX4D,
  • HOX4D,
  • NM_002148,
  • HOX4E,
  • HOX4,
  • homeo box D10,
  • HGNC:5133
  • identifiers:
  • 3236,
  • ENSG00000128710,
  • HOXD10

Genome feature

Region: gene ? Length: 3160  
Location: 2:176116778-176119937 Cyto location: 2q31.1


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

290 SN Ps

5 Cross References

18 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results