help  | about  | cite  | software

Gene : HPGD Homo sapiens
Name  ? 15-hydroxyprostaglandin dehydrogenase Cytological Location  4q34.1
Brief Description  15-hydroxyprostaglandin dehydrogenase
description  This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • synonyms:
  • NM_000860,
  • HGNC:5154,
  • SDR36C1,
  • short chain dehydrogenase/reductase family 36C, member 1,
  • SDR36C1,
  • PGDH1,
  • 15-PGDH,
  • PHOAR1,
  • uc003itu.3,
  • HPGD,
  • hydroxyprostaglandin dehydrogenase 15-(NAD),
  • 15-hydroxyprostaglandin dehydrogenase (NAD(+)),
  • OTTHUMG00000160772,
  • PGDH
  • identifiers:
  • 3248,
  • ENSG00000164120,
  • HPGD

Genome feature

Region: gene ? Length: 32724  
Location: 4:174490175-174522898 reverse strand Cyto location: 4q34.1


Paste the following link

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

11 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

11 Pathways

937 SN Ps

5 Cross References

18 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results





Funding: InterMine has been developed principally through support of the Wellcome Trust. Complementary projects have been funded by the NIH/NHGRI and the BBSRC.

An ELIXIR-UK resource

© 2002 - 2019 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom