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Gene : HPGD Homo sapiens

Name  ? 15-hydroxyprostaglandin dehydrogenase Cytological Location  4q34.1
Brief Description  15-hydroxyprostaglandin dehydrogenase
Description  This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • synonyms:
  • 15-hydroxyprostaglandin dehydrogenase (NAD(+)),
  • PGDH,
  • PGDH1,
  • uc003itu.3,
  • NM_000860,
  • HGNC:5154,
  • HPGD,
  • hydroxyprostaglandin dehydrogenase 15-(NAD),
  • OTTHUMG00000160772,
  • 15-PGDH,
  • SDR36C1,
  • SDR36C1,
  • short chain dehydrogenase/reductase family 36C, member 1,
  • PHOAR1
  • identifiers:
  • 3248,
  • ENSG00000164120,
  • HPGD

Genome feature

Region: gene ? Length: 32719  
Location: 4:174490175-174522893 reverse strand Cyto location: 4q34.1

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2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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937 SN Ps

5 Cross References

17 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results