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Gene : APCS Homo sapiens

Name  ? amyloid P component, serum Cytological Location  1q23.2
Brief Description  amyloid P component, serum
Description  The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]
  • synonyms:
  • OTTHUMG00000022741,
  • pentraxin-2,
  • PTX2,
  • PTX2,
  • HGNC:584,
  • APCS,
  • uc001ftv.4,
  • MGC88159,
  • pentraxin-related,
  • SAP,
  • 9.5S alpha-1-glycoprotein,
  • SAP,
  • HEL-S-92n,
  • NM_001639
  • identifiers:
  • 325,
  • ENSG00000132703,
  • APCS

Genome feature

Region: gene ? Length: 1040  
Location: 1:159587826-159588865 Cyto location: 1q23.2

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



58 SN Ps

5 Cross References

15 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results