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Gene : BIRC2 Homo sapiens

Name  ? baculoviral IAP repeat containing 2 Cytological Location  11q22.2
Brief Description  baculoviral IAP repeat containing 2
Description  The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • synonyms:
  • BIRC2,
  • c-IAP1,
  • HIAP2,
  • OTTHUMG00000167325,
  • API1,
  • MIHB,
  • c-IAP1,
  • cIAP1,
  • apoptosis inhibitor 1,
  • MIHB,
  • uc001pgy.5,
  • API1,
  • L49431,
  • baculoviral IAP repeat-containing 2,
  • RNF48,
  • hiap-2,
  • HGNC:590,
  • cIAP1,
  • Hiap-2,
  • RNF48,
  • NM_001166,
  • NFR2-TRAF signalling complex protein
  • identifiers:
  • 329,
  • ENSG00000110330,
  • BIRC2

Genome feature

Region: gene ? Length: 31457  
Location: 11:102347214-102378670 Cyto location: 11q22.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

375 SNPs

5 Cross References

14 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results