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Gene : BIRC3 Homo sapiens

Name  ? baculoviral IAP repeat containing 3 Cytological Location  11q22.2
Brief Description  baculoviral IAP repeat containing 3
Description  This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]
  • synonyms:
  • apoptosis inhibitor 2,
  • IAP-1,
  • API2,
  • c-IAP2,
  • L49432,
  • RNF49,
  • CIAP2,
  • MALT2,
  • baculoviral IAP repeat-containing 3,
  • MIHC,
  • MALT2,
  • API2,
  • uc058guu.1,
  • HGNC:591,
  • NM_001165,
  • AIP1,
  • mammalian IAP homolog C,
  • HAIP1,
  • MIHC,
  • TNFR2-TRAF signaling complex protein,
  • RNF49,
  • BIRC3,
  • HIAP1,
  • hiap-1,
  • OTTHUMG00000167324,
  • cIAP2,
  • inhibitor of apoptosis protein 1,
  • c-IAP2
  • identifiers:
  • 330,
  • ENSG00000023445,
  • BIRC3

Genome feature

Region: gene ? Length: 22031  
Location: 11:102317373-102339403 Cyto location: 11q22.2

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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751 SNPs

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results