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Gene : BIRC5 Homo sapiens

Name  ? baculoviral IAP repeat containing 5 Cytological Location  17q25.3
Brief Description  baculoviral IAP repeat containing 5
Description  This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
  • synonyms:
  • baculoviral IAP repeat-containing 5,
  • survivin,
  • API4,
  • BIRC5,
  • OTTHUMG00000177505,
  • EPR-1,
  • survivin variant 3 alpha,
  • U75285,
  • HGNC:593,
  • NM_001168,
  • EPR-1,
  • API4,
  • apoptosis inhibitor 4,
  • uc002jvg.4
  • identifiers:
  • 332,
  • ENSG00000089685,
  • BIRC5

Genome feature

Region: gene ? Length: 11383  
Location: 17:78214253-78225635 Cyto location: 17q25.3

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



462 SNPs

5 Cross References

16 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results