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Gene : APLP1 Homo sapiens

Name  ? amyloid beta precursor like protein 1 Cytological Location  19q13.12
Brief Description  amyloid beta precursor like protein 1
Description  This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • synonyms:
  • amyloid beta (A4) precursor-like protein 1,
  • APLP1,
  • APLP,
  • uc002ocf.4,
  • NM_001024807,
  • U48437,
  • amyloid precursor-like protein 1,
  • OTTHUMG00000180692,
  • HGNC:597,
  • amyloid-like protein 1,
  • APLP
  • identifiers:
  • 333,
  • ENSG00000105290,
  • APLP1

Genome feature

Region: gene ? Length: 11226  
Location: 19:35868570-35879795 Cyto location: 19q13.12

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3740 SNPs

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results