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Gene : HTR2A Homo sapiens

Name  ? 5-hydroxytryptamine receptor 2A Cytological Location  13q14.2
Brief Description  5-hydroxytryptamine receptor 2A
Description  This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • synonyms:
  • X57830,
  • uc010acr.5,
  • OTTHUMG00000016881,
  • 5-HT2A,
  • 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled,
  • HTR2,
  • HTR2,
  • NM_000621,
  • 5-hydroxytryptamine (serotonin) receptor 2A,
  • HTR2A,
  • HGNC:5293,
  • 5-HT2A
  • identifiers:
  • 3356,
  • ENSG00000102468,
  • HTR2A

Genome feature

Region: gene ? Length: 66537  
Location: 13:46831546-46898082 reverse strand Cyto location: 13q14.2

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Report --> GWAS hit


5 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results