help  | about  | cite  | software

Gene : HTR2B Homo sapiens

Name  ? 5-hydroxytryptamine receptor 2B Cytological Location  2q37.1
Brief Description  5-hydroxytryptamine receptor 2B
Description  This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
  • synonyms:
  • 5-hydroxytryptamine (serotonin) receptor 2B,
  • 5-HT(2B),
  • HTR2B,
  • 5-HT(2B),
  • NM_000867,
  • 5-HT-2B,
  • 5-HT2B,
  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled,
  • uc002vro.4,
  • OTTHUMG00000133222,
  • 5-HT2B,
  • HGNC:5294
  • identifiers:
  • 3357,
  • ENSG00000135914,
  • HTR2B

Genome feature

Region: gene ? Length: 17943  
Location: 2:231108230-231126172 reverse strand Cyto location: 2q37.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

17 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results