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Gene : CLEC4G Homo sapiens

Name  ? C-type lectin domain family 4 member G Cytological Location  19p13.2
Brief Description  C-type lectin domain family 4 member G
Description  This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as well as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020]
  • synonyms:
  • HGNC:24591,
  • UNQ431,
  • LSECtin,
  • LSECtin,
  • UNQ431,
  • LP2698,
  • CLEC4G,
  • uc002mhp.4,
  • DTTR431,
  • C-type lectin domain family 4, member G,
  • C-type lectin superfamily 4, member G,
  • AY358431,
  • OTTHUMG00000182519,
  • NM_198492
  • identifiers:
  • 339390,
  • ENSG00000182566,
  • CLEC4G

Genome feature

Region: gene ? Length: 3225  
Location: 19:7728957-7732181 reverse strand Cyto location: 19p13.2


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Function

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

375 SN Ps

5 Cross References

15 Data Sets

17 Homologues

0 Located Features

97 Rna Seq Results