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Gene : APOE Homo sapiens

Name  ? apolipoprotein E Cytological Location  19q13.32
Brief Description  apolipoprotein E
Description  The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
  • synonyms:
  • LPG,
  • K00396,
  • uc002pab.4,
  • Alzheimer disease 2 (APOE*E4-associated, late onset),
  • AD2,
  • NM_000041,
  • APO-E,
  • LDLCQ5,
  • APOE,
  • AD2,
  • ApoE4,
  • HGNC:613,
  • OTTHUMG00000128901
  • identifiers:
  • 348,
  • ENSG00000130203,
  • APOE

Genome feature

Region: gene ? Length: 3598  
Location: 19:44905796-44909393 Cyto location: 19q13.32

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Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


7 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



401 SNPs

5 Cross References

19 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results