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Gene : IGF1R Homo sapiens

Name  ? insulin like growth factor 1 receptor Cytological Location  15q26.3
Brief Description  insulin like growth factor 1 receptor
Description  This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
  • synonyms:
  • JTK13,
  • HGNC:5465,
  • IGF1R,
  • IGFR,
  • NM_000875,
  • CD221,
  • MGC18216,
  • M69229,
  • IGFIR,
  • OTTHUMG00000149851,
  • IGFIR,
  • JTK13,
  • insulin-like growth factor 1 receptor,
  • CD221,
  • uc002bul.4,
  • IGFR
  • identifiers:
  • 3480,
  • ENSG00000140443,
  • IGF1R

Genome feature

Region: gene ? Length: 315992  
Location: 15:98648539-98964530 Cyto location: 15q26.3

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Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



537 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results