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Gene : IGFBP3 Homo sapiens

Name  ? insulin like growth factor binding protein 3 Cytological Location  7p12.3
Brief Description  insulin like growth factor binding protein 3
Description  This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_001013398,
  • binding protein 29,
  • uc003tns.4,
  • BP-53,
  • insulin-like growth factor binding protein 3,
  • binding protein 53,
  • IBP3,
  • IBP3,
  • growth hormone-dependent binding protein,
  • BP-53,
  • IGF-binding protein 3,
  • acid stable subunit of the 140 K IGF complex,
  • HGNC:5472,
  • IGFBP3,
  • OTTHUMG00000023769
  • identifiers:
  • 3486,
  • ENSG00000146674,
  • IGFBP3

Genome feature

Region: gene ? Length: 9028  
Location: 7:45912245-45921272 reverse strand Cyto location: 7p12.3


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405 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results