help  | about  | cite  | software

Gene : IGFBP3 Homo sapiens

Name  ? insulin like growth factor binding protein 3 Cytological Location  7p12.3
Brief Description  insulin like growth factor binding protein 3
Description  This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_001013398,
  • binding protein 29,
  • uc003tns.4,
  • BP-53,
  • insulin-like growth factor binding protein 3,
  • binding protein 53,
  • IBP3,
  • IBP3,
  • growth hormone-dependent binding protein,
  • BP-53,
  • IGF-binding protein 3,
  • acid stable subunit of the 140 K IGF complex,
  • HGNC:5472,
  • IGFBP3,
  • OTTHUMG00000023769
  • identifiers:
  • 3486,
  • ENSG00000146674,
  • IGFBP3

Genome feature

Region: gene ? Length: 9028  
Location: 7:45912245-45921272 reverse strand Cyto location: 7p12.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



405 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results