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Gene : CXCL8 Homo sapiens

Name  ? C-X-C motif chemokine ligand 8 Cytological Location  4q13.3
Brief Description  C-X-C motif chemokine ligand 8
Description  The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is secreted primarily by neutrophils, where it serves as a chemotactic factor by guiding the neutrophils to the site of infection. This chemokine is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other members of the CXC chemokine gene family form a gene cluster in a region of chromosome 4q. [provided by RefSeq, Aug 2017]
  • synonyms:
  • IL8,
  • lymphocyte derived neutrophil activating peptide,
  • MONAP,
  • GCP1,
  • CXCL8,
  • NAP1,
  • LYNAP,
  • IL8,
  • monocyte-derived neutrophil chemotactic factor,
  • GCP-1,
  • NAP-1,
  • tumor necrosis factor-induced gene 1,
  • LYNAP,
  • LUCT,
  • MONAP,
  • NAP1,
  • LUCT,
  • MDNCF,
  • NM_000584,
  • b-ENAP,
  • HGNC:6025,
  • LECT,
  • IL-8,
  • AMCF-I,
  • monocyte-derived neutrophil-activating peptide,
  • NAF,
  • 3-10C,
  • GCP-1,
  • beta endothelial cell-derived neutrophil activating peptide,
  • TSG-1,
  • LECT,
  • OTTHUMG00000151316,
  • Y00787,
  • MDNCF,
  • chemokine (C-X-C motif) ligand 8,
  • GCP1,
  • granulocyte chemotactic protein 1,
  • lung giant cell carcinoma-derived chemotactic protein,
  • NAF,
  • interleukin 8,
  • alveolar macrophage chemotactic factor I,
  • K60,
  • NAP-1,
  • SCYB8,
  • neutrophil-activating peptide 1
  • identifiers:
  • 3576,
  • ENSG00000169429,
  • CXCL8

Genome feature

Region: gene ? Length: 3148  
Location: 4:73740569-73743716 Cyto location: 4q13.3


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0 Diseases

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Other

290 SN Ps

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results