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Gene : ITGA2 Homo sapiens

Name  ? integrin subunit alpha 2 Cytological Location  5q11.2
Brief Description  integrin subunit alpha 2
Description  This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
  • synonyms:
  • HPA-5,
  • CD49b,
  • NM_002203,
  • VLA-2,
  • uc003joy.3,
  • integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor),
  • CD49B,
  • alpha 2 subunit of VLA-2 receptor,
  • HGNC:6137,
  • OTTHUMG00000131165,
  • BR,
  • CD49B,
  • GPIa,
  • VLAA2,
  • ITGA2
  • identifiers:
  • 3673,
  • ENSG00000164171,
  • ITGA2

Genome feature

Region: gene ? Length: 105428  
Location: 5:52989352-53094779 Cyto location: 5q11.2

Uni Prot Comments Displayer

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Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results