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Gene : ITGA3 Homo sapiens

Name  ? integrin subunit alpha 3 Cytological Location  17q21.33
Brief Description  integrin subunit alpha 3
Description  The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
  • synonyms:
  • MSK18,
  • NM_005501,
  • ILNEB,
  • M59911,
  • HGNC:6139,
  • GAP-B3,
  • VCA-2,
  • FRP-2,
  • MSK18,
  • antigen CD49C,
  • integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor),
  • GAP-B3,
  • VL3A,
  • OTTHUMG00000161890,
  • VLA3a,
  • ITGA3,
  • CD49c,
  • GAPB3,
  • VLA3a,
  • alpha 3 subunit of VLA-3 receptor,
  • antigen identified by monoclonal antibody J143,
  • VCA-2,
  • CD49C,
  • uc010dbl.4
  • identifiers:
  • 3675,
  • ENSG00000005884,
  • ITGA3

Genome feature

Region: gene ? Length: 34417  
Location: 17:50056065-50090481 Cyto location: 17q21.33

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



366 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results