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Gene : ITGAV Homo sapiens

Name  ? integrin subunit alpha V Cytological Location  2q32.1
Brief Description  integrin subunit alpha V
Description  The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
  • synonyms:
  • ITGAV,
  • VNRA,
  • uc002upq.5,
  • OTTHUMG00000132635,
  • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51),
  • VNRA,
  • NM_002210,
  • VTNR,
  • MSK8,
  • CD51,
  • MSK8,
  • antigen identified by monoclonal antibody L230,
  • integrin, alpha V,
  • vitronectin receptor,
  • CD51,
  • HGNC:6150,
  • VTNR
  • identifiers:
  • 3685,
  • ENSG00000138448,

Genome feature

Region: gene ? Length: 90847  
Location: 2:186590056-186680902 Cyto location: 2q32.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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3753 SN Ps

5 Cross References

17 Data Sets

5 Homologues

2 Located Features

97 Rna Seq Results