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Gene : ITGB2 Homo sapiens

Name  ? integrin subunit beta 2 Cytological Location  21q22.3
Brief Description  integrin subunit beta 2
Description  This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
  • synonyms:
  • integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit),
  • complement component 3 receptor 3 and 4 subunit,
  • MFI7,
  • MF17,
  • HGNC:6155,
  • LFA-1,
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit),
  • MAC-1,
  • LCAMB,
  • LAD,
  • MAC-1,
  • MFI7,
  • NM_000211,
  • AK222505,
  • CD18,
  • uc002zgf.5,
  • CD18,
  • ITGB2,
  • LFA-1,
  • OTTHUMG00000090257
  • identifiers:
  • 3689,
  • ENSG00000160255,
  • ITGB2

Genome feature

Region: gene ? Length: 42867  
Location: 21:44885949-44928815 reverse strand Cyto location: 21q22.3


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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

453 SN Ps

5 Cross References

19 Data Sets

7 Homologues

2 Located Features

97 Rna Seq Results