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Gene : CD82 Homo sapiens

Name  ? CD82 molecule Cytological Location  11p11.2
Brief Description  CD82 molecule
Description  This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • KAI1,
  • C33,
  • HGNC:6210,
  • TSPAN27,
  • 4F9,
  • R2 leukocyte antigen,
  • IA4,
  • R2,
  • KAI1,
  • R2,
  • GR15,
  • kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)),
  • ST6,
  • TSPAN27,
  • suppression of tumorigenicity 6,
  • U20770,
  • ST6,
  • NM_002231,
  • IA4,
  • CD82 antigen,
  • CD82,
  • uc001myc.4,
  • OTTHUMG00000166472,
  • SAR2
  • identifiers:
  • 3732,
  • ENSG00000085117,
  • CD82

Genome feature

Region: gene ? Length: 54754  
Location: 11:44565610-44620363 Cyto location: 11p11.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

503 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results