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Gene : AREG Homo sapiens

Name  ? amphiregulin Cytological Location  4q13.3
Brief Description  amphiregulin
Description  The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
  • synonyms:
  • CRDGF,
  • uc032tme.2,
  • SDGF,
  • AR,
  • SDGF,
  • AREGB,
  • schwannoma-derived growth factor,
  • M30704,
  • NM_001657,
  • amphiregulin B,
  • OTTHUMG00000130006,
  • AREGB,
  • HGNC:651,
  • AREG
  • identifiers:
  • 374,
  • ENSG00000109321,
  • AREG

Genome feature

Region: gene ? Length: 9870  
Location: 4:74445136-74455005 Cyto location: 4q13.3

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



805 SNPs

5 Cross References

15 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results