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Gene : ASIC2 Homo sapiens

Name  ? acid sensing ion channel subunit 2 Cytological Location  17q11.2-q12
Brief Description  acid sensing ion channel subunit 2
Description  This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]
  • synonyms:
  • ASIC2a,
  • hBNaC1,
  • HGNC:99,
  • BNC1,
  • ASIC2a,
  • ACCN,
  • AL834182,
  • ACCN,
  • NM_183377,
  • OTTHUMG00000132885,
  • BNC1,
  • degenerin,
  • BNaC1,
  • MDEG,
  • ACCN1,
  • amiloride-sensitive cation channel 1, neuronal,
  • NM_001094,
  • ASIC2,
  • ACCN1,
  • MDEG,
  • BNaC1,
  • acid-sensing (proton-gated) ion channel 2,
  • uc002hhu.4,
  • hBNaC1
  • identifiers:
  • 40,
  • ENSG00000108684,
  • ASIC2

Genome feature

Region: gene ? Length: 1143682  
Location: 17:33013087-34156768 reverse strand Cyto location: 17q11.2-q12

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219 SNPs

5 Cross References

17 Data Sets

46 Homologues

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97 Rna Seq Results