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Gene : ARNT Homo sapiens

Name  ? aryl hydrocarbon receptor nuclear translocator Cytological Location  1q21.3
Brief Description  aryl hydrocarbon receptor nuclear translocator
Description  This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
  • synonyms:
  • NM_001197325,
  • HGNC:700,
  • HIF1B,
  • HIF1BETA,
  • bHLHe2,
  • HIF-1beta,
  • AF001307,
  • HIF-1-beta,
  • HIF1-beta,
  • TANGO,
  • bHLHe2,
  • uc001evr.2,
  • ARNT,
  • OTTHUMG00000035011,
  • HIF-1beta
  • identifiers:
  • 405,
  • ENSG00000143437,
  • ARNT

Genome feature

Region: gene ? Length: 67025  
Location: 1:150809713-150876737 reverse strand Cyto location: 1q21.3


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3756 SN Ps

5 Cross References

17 Data Sets

7 Homologues

3 Located Features

97 Rna Seq Results