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Gene : CYP4F3 Homo sapiens

Name  ? cytochrome P450 family 4 subfamily F member 3 Cytological Location  19p13.12
Brief Description  cytochrome P450 family 4 subfamily F member 3
Description  This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2019]
  • synonyms:
  • CYP4F,
  • cytochrome P450, family 4, subfamily F, polypeptide 3,
  • LTB4H,
  • AB002454,
  • NM_000896,
  • CYP4F,
  • uc002nbj.4,
  • LTB4H,
  • HGNC:2646,
  • CYPIVF3,
  • CYP4F3,
  • CPF3,
  • OTTHUMG00000182374,
  • cytochrome P450, subfamily IVF, polypeptide 3 (leukotriene B4 omega hydroxylase)
  • identifiers:
  • 4051,
  • ENSG00000186529,
  • CYP4F3

Genome feature

Region: gene ? Length: 21929  
Location: 19:15640897-15662825 Cyto location: 19p13.12

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SN Ps

5 Cross References

15 Data Sets

18 Homologues

0 Located Features

97 Rna Seq Results